Genetically engineered immune privileged Sertoli cells
نویسندگان
چکیده
منابع مشابه
Genetically engineered immune privileged Sertoli cells
Sertoli cells are immune privileged cells, important for controlling the immune response to male germ cells as well as maintaining the tolerogenic environment in the testis. Additionally, ectopic Sertoli cells have been shown to survive and protect co-grafted cells when transplanted across immunological barriers. The survival of ectopic Sertoli cells has led to the idea that they could be used ...
متن کاملTherapeutic potential of immune privileged Sertoli cells
Sertoli Cells (SCs) in the testes have evolved to possess unique immune privileged properties to protect the developing germ cells from immunological attack. These immune privileged properties are not restricted to the testis, as SCs survive when transplanted across immunological barriers as alloand xeno-grafts. Here we discuss the therapeutic potential of transplanted SCs in protecting cells, ...
متن کاملGenetically Engineered Mesenchymal Stem Cells Stably Expressing Green Fluorescent Protein
Objective(s) Mesenchymal stem cells (MSCs) are nonhematopoietic stromal cells that are capable of differentiating into and contribute to the regeneration of mesenchymal tissues. Human mesenchymal stem cells (hMSCs) are ideal targets in cell transplantation and tissue engineering. Enhanced green fluorescent protein (EGFP) has been an important reporter gene for gene therapy. The aim of this stu...
متن کاملgenetically engineered mesenchymal stem cells stably expressing green fluorescent protein
objective(s) mesenchymal stem cells (mscs) are nonhematopoietic stromal cells that are capable of differentiating into and contribute to the regeneration of mesenchymal tissues. human mesenchymal stem cells (hmscs) are ideal targets in cell transplantation and tissue engineering. enhanced green fluorescent protein (egfp) has been an important reporter gene for gene therapy. the aim of this stud...
متن کاملInitial in vitro investigation of the human immune response to corneal cells from genetically engineered pigs.
PURPOSE To compare the in vitro human humoral and cellular immune responses to wild-type (WT) pig corneal endothelial cells (pCECs) with those to pig aortic endothelial cells (pAECs). These responses were further compared with CECs from genetically engineered pigs (α1,3-galactosyltransferase gene-knockout [GTKO] pigs and pigs expressing a human complement-regulatory protein [CD46]) and human do...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Spermatogenesis
سال: 2012
ISSN: 2156-5562
DOI: 10.4161/spmg.19119